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  • A new drug approved for weight-loss by the U.S. Food and Drug Administration had great results in clinical trials, however it isn't a panacea for weight reduction. It must be found in combination with a low-calorie diet and physical exercise in order to be effective.

    Using two separate drugs to lose weight can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you should err on the side of caution and allow FDA do its job and demand some research be done in order that the public recognizes the side effects and risks of the medications before we drive them. Keep in mind that drug companies will be in business to make money and that they would say almost anything to keep people on their own medications.

    Researchers found out that participants investing in this drug for a year, lost excess weight within four weeks and have kept the extra weight off through the 56 weeks from the study. Contrave can be a combination from the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs that are made up of multiple active ingredient, which can make them more potent and safer.

    Combo-pilling may be the newest fad or better yet the newest to come under scrutiny and thus it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular could be the fact that since right now there are not any long term prescription slimming capsules that have been licensed by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be authorized by the FDA.

    Seizures certainly are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug can also raise hypertension and heartbeat, and must not be used in people with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise hypertension and pulse rate and must 't be used in patients with uncontrolled high blood pressure level, and also by you aren't heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients using a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients for the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.

    "This is the first drug I'm mindful of that targets both the appetite and reward centres in the brain," he said.

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