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What if you had been a problem drinker or alcoholic, along with a medical professional could give you a drug to adopt away your urge to drink—while you were still permitted continue drinking? Advocates on this treatment approach, known as the Sinclair method, claim you'd likely experience no withdrawal symptoms. According to proponents, after 3 or 4 months on the medication, all while still being capable of continue to drink, you'd experience diminished cravings or perhaps find that your urge to drink disappears altogether.

Using two separate drugs to shed weight can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you need to err along the side of caution and allow FDA do its job and demand some research be done so the public knows the side effects and dangers of the medications before we take them. Keep in mind that drug companies have been in business to generate income and that they would say almost anything to keep people on the medications.

Researchers found out that participants taking this drug for the year, dropped excess weight within a month and have kept the load off through the entire 56 weeks of the study. Contrave is a combination in the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which might be made up of many active ingredient, which can make them more potent and safer.

Combo-pilling will be the newest fad or better yet the newest into the future under scrutiny and for that reason it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills is becoming popular could be the fact that as of right now there are no long term prescription diet pills that have been authorized by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be licensed by the FDA.

Seizures certainly are a side effect with Contrave and must not be taken in those with seizure disorders. The drug may also raise hypertension and heart rate, and must not be used in people who have a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure level and pulse rate and must not be used in patients with uncontrolled high blood pressure levels, as well as by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients having a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients to the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking.

"There were no warning signs of depression or suicidal thoughts in trial participants," said Fujioka.